What is Gene Ontology?
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Gene ontology (GO) is an online database that categorizes the function of genes and gene products. GO describes gene function through three areas of observation: Cellular Component, Molecular Function, and Biological Processes [1].
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Gene Ontology of ABCA12
Cellular Component
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Molecular Function
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Biological Processes
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Discussion
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Gene ontology is a useful tool for understanding the ABCA12 gene further. Its location, function, and processes as defined by GO help characterize it as a lipid transport gene involved in the establishment and keratin shedding of the epidermis, implicating its role in harlequin ichthyosis disease.
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References:
[1]. Gene Ontology Overview. Retrieved from http://geneontology.org/page/ontology-documentation |
Image References:
Cell diagram: https://en.wikibooks.org/wiki/IGCSE_Science/Section_2:_Structures_and_functions_in_living_organisms/Cell_structure Transport diagram: http://flipper.diff.org/app/items/info/3254 Lipid bilayer diagram: https://www.researchgate.net/figure/Structure-of-the-cell-membrane_fig1_329187565 |
This web page was produced as an assignment for Genetics 564, an undergraduate capstone course at UW-Madison